- Title
- Whole-genome sequencing to differentiate relapse from reinfection in community-onset bacteremic Acinetobacter baumannii pneumonia
- Creator
- Meumann, Ella M.; Anstey, Nicholas M.; Currie, Bart J.; Piera, Kim A.; Baird, Robert; Sarovich, Derek S.; Davis, Joshua S.
- Relation
- NHMRC.1114696 http://purl.org/au-research/grants/nhmrc/1114696
- Relation
- Open Forum Infectious Diseases Vol. 6, Issue 7, p. 1-4
- Publisher Link
- http://dx.doi.org/10.1093/ofid/ofz263
- Publisher
- Oxford University Press
- Resource Type
- journal article
- Date
- 2019
- Description
- Community-onset bacteremic Acinetobacter baumannii pneumonia recurred in 3 of 30 (10%) patients followed prospectively, all with ongoing hazardous alcohol intake, 3-56 months after initial pneumonia. Paired isolates underwent whole-genome sequencing. Phylogenetic analysis showed that recurrence strains were all distinct from preceding strains, indicating reinfection in susceptible individuals rather than relapse.
- Subject
- Acinetobacter baumannii; community-acquired pneumonia; recurrence; relapse; whole-genome sequencing; SDG 3; Sustainable Development Goals
- Identifier
- http://hdl.handle.net/1959.13/1456276
- Identifier
- uon:45198
- Identifier
- ISSN:2328-8957
- Rights
- Copyright © The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution- NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
- Language
- eng
- Full Text
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